Giannitsis E, Spanuth E, Horsch A, Kleber ME, Koch W, Grammer TB, Koenig W, März W
In 1,469 LURIC patients with stable CAD followed for a median 7.5 years, 35% died. High-sensitivity cardiac troponin T (hscTnT; optimal cut-off 14 ng/L, AUC 0.725) and NT-proBNP (443 µg/L, AUC 0.742) were independent mortality predictors, and their combined assessment improved reclassification by an NRI of 24.2%, particularly for 1-year mortality. Simultaneous measurement of both biomarkers outperforms either marker alone for risk stratification in stable coronary artery disease.
Clinical Chemistry and Laboratory Medicine, Oktober 2013 | PMID 24072576