Karakas M, Hoffmann MM, Vollmert C, Rothenbacher D, Meisinger C, Winkelmann B, Khuseyinova N, Böhm BO et al.
FcgammaRIIa-R/H131 polymorphisms were genotyped in two independent populations – the MONICA-Augsburg survey (527 myocardial infarction cases, 527 controls) and the LURIC cohort (2,227 CHD patients vs. 1,032 individuals with stenosis <50%) – to test for an association with coronary heart disease risk. After multivariable adjustment, FcgammaRIIa genotype was not independently associated with CHD in either population (LURIC OR 0.96, 95% CI 0.81-1.14), indicating that this receptor variant does not meaningfully influence CHD susceptibility.
BMC Medical Genetics, 29. Mai 2009 | PMID 19480687