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LURIC

Publikation · PMID 24569029

Low-density lipoprotein particle diameter and mortality: the Ludwigshafen Risk and Cardiovascular Health Study

Grammer TB, Kleber ME, März W, Silbernagel G, Siekmeier R, Wieland H, Pilz S, Tomaschitz A et al.

LDL particle diameter and total and cardiovascular mortality were assessed in 1,643 LURIC participants not on lipid-lowering drugs over a median 9.9-year follow-up. Both large (>16.8 nm) and small (<16.5 nm) LDL independently predicted higher cardiovascular mortality than intermediate-diameter LDL (HR 1.89 and 1.54, respectively). Large LDL was characterised by elevated IL-6 and CRP, suggesting distinct inflammatory profiles across LDL size categories.

European Heart Journal, 25. Februar 2014 | PMID 24569029

Zeitschrift
European Heart Journal
DOI
10.1093/eurheartj/ehu055
PMID
24569029
Quelle
https://pubmed.ncbi.nlm.nih.gov/24569029/
Zitationen
34 Relative Zitationsrate 1.35 (1,0 = Durchschnitt des Fachgebiets) · NIH iCite, Stand 20.08.2026