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LURIC

Publikation · PMID 27667446

Oxidized LDL, statin use, morbidity, and mortality in patients receiving maintenance hemodialysis

Wagner S, Apetrii M, Massy ZA, Kleber ME, Delgado GE, Scharnagel H, März W, Metzger M et al.

Associations between oxidized LDL (oxLDL) and cardiovascular outcomes were examined in hemodialysis patients from the AURORA trial and non-hemodialysis patients from the LURIC cohort. Baseline oxLDL (34.2 +/- 13.8 U/L in AURORA; 74.6 +/- 28.1 U/L in LURIC) was not independently associated with MACE or all-cause mortality after adjustment for apolipoprotein B, and a rosuvastatin-induced oxLDL reduction of 30.9% at three months conferred no significant outcome benefit.

Free Radical Research, 25. Januar 2017 | PMID 27667446

Zeitschrift
Free Radical Research
DOI
10.1080/10715762.2016.1241878
PMID
27667446
Quelle
https://pubmed.ncbi.nlm.nih.gov/27667446/